Polycystins, calcium signaling and pathogenesis of polycystic kidney disease

Bibliographic Details
Main Author: Del Senno, Laura
Format: eBook
Language:English
Published: London Henry Stewart Talks 2007, 2007
Series:Calcium signaling I : regulation, mechanisms, effectors, role in disease and recent advances
Subjects:
Online Access:
Collection: Henry Stewart Talks - Collection details see MPG.ReNa
Table of Contents:
  • Clinical and genetic aspects of polycystic kidney disease
  • The polycystins (PC1, PC2)
  • The PC2 channel
  • PC1 and PC2 subcellular location and interaction
  • Mechanosensory function of the ciliary PC1/PC2 complex
  • PC signaling and calcium homeostasis
  • PC1, calcium levels and cell proliferation
  • PC1, cAMP signaling and cell proliferation
  • PCs and physiopathologic calcium signaling