Chemokines and inflammation a critical assessment of therapeutic targets

Bibliographic Details
Main Author: Greaves, David R.
Format: eBook
Language:English
Published: London Henry Stewart Talks 2009, 2009
Series:Innate immunity : host recognition and response in health and disease
Subjects:
Online Access:
Collection: Henry Stewart Talks - Collection details see MPG.ReNa
Table of Contents:
  • Introduction to chemokine biology
  • Chemokine receptors
  • Decoy chemokine receptors
  • Chemokine evolution
  • Chemokine function
  • Acute and chronic inflammation
  • Chronic inflammatory diseases
  • Chemokines and leukocyte recruitment
  • Chemokine function in atherosclerosis
  • CCL2 acting via CCR2
  • CCL3, 4, 5 acting via CCR1 and CCR5
  • CXCL9, 10, 11 acting via CXCR3
  • CX3CL1 acting via CX3CR1
  • Targeting chemokines in atherosclerosis and other forms of inflammation
  • Neutralising antibodies
  • Small molecule inhibitors
  • Mutant chemokines
  • Broad-spectrum chemokine blockade