Antigen processing and presentation modulation by innate immune signals
| Main Author: | |
|---|---|
| Format: | eBook |
| Language: | English |
| Published: |
London
Henry Stewart Talks
2009, 2009
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| Series: | Innate immunity : host recognition and response in health and disease
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| Subjects: | |
| Online Access: | |
| Collection: | Henry Stewart Talks - Collection details see MPG.ReNa |
Table of Contents:
- Conventional and non-conventional antigen processing pathways
- Innate stimuli boost antigen capture, processing and presentation
- Destructive antigen processing is minimised in dendritic cells (DC)
- Class II MHC display is regulated by ubiquitination
- Linking antigens and TLR ligands can enhance presentation
- Distinct endocytic compartments and/or distinct dendritic cell sub-sets may host antigen presentation on class I MHC molecules (cross-presentation) and on class II MHC molecules
- Antigen bearing migratory DC and lymph node resident DC can collaborate to induce T cell responses