Lipids in Protein Misfolding

This book addresses molecular mechanisms of protein misfolding and the role of lipids and related molecules in these complex processes. The focus is on the biophysical and structural studies of proteins that are involved in major human disorders such as Alzheimer’s disease, systemic amyloidoses, dia...

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Bibliographic Details
Other Authors: Gursky, Olga (Editor)
Format: eBook
Language:English
Published: Cham Springer International Publishing 2015, 2015
Edition:1st ed. 2015
Series:Advances in Experimental Medicine and Biology
Subjects:
Online Access:
Collection: Springer eBooks 2005- - Collection details see MPG.ReNa
Table of Contents:
  • Role of Lipids in Folding, Misfolding and Function of Integral Membrane Proteins
  • Protein Misfolding in Lipid-Mimetic Environments.- Lipids in Amyloid-β Processing, Aggregation, and Toxicity
  • Role of Cholesterol and Phospholipids in Amylin Misfolding, Aggregation and Etiology of Islet Amyloidosis
  • Stability, Oligomerization, and Amyloidogenicity of Apo Serum Amyloid A
  • Interactions of Lipid Membranes with Fibrillar Protein Aggregates
  • The Role of Lipid in Misfolding and Amyloid Fibril Formation by Apolipoprotein C-II
  • Amyloid-Forming Properties of Human Apolipoproteins: Sequence Analyses and Structural Insights
  • Computational Approaches to Identification of Aggregation Sites and the Mechanism of Amyloid Growth
  • Role of Syndecans in Lipid Metabolism and Human Diseases