Prophylactic treatment for contacts of patients with invasive meningococcal disease on sports teams : a review of the clinical effectiveness, cost-effectiveness, and guidelines

Invasive meningococcal disease (IMD) is a potentially life threatening infectious disease caused by the gram-negative aerobic diplococcus, Neisseria (N.) meningitidis. Transmission of N. meningitidis occurs through respiratory droplets or direct contact with nasopharyngeal secretions while the usual...

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Corporate Author: Canadian Agency for Drugs and Technologies in Health
Format: eBook
Language:English
Published: [Ottawa] Canadian Agency for Drugs and Technologies in Health 10 February 2015, 2015
Series:Rapid response report: summary with critical appraisal
Subjects:
Online Access:
Collection: National Center for Biotechnology Information - Collection details see MPG.ReNa
Summary:Invasive meningococcal disease (IMD) is a potentially life threatening infectious disease caused by the gram-negative aerobic diplococcus, Neisseria (N.) meningitidis. Transmission of N. meningitidis occurs through respiratory droplets or direct contact with nasopharyngeal secretions while the usual incubation period is 3 to 4 days. To limit the spread of IMD, chemoprophylaxis with or without immunoprophylaxis is offered to contacts with the goal of eliminating N. meningitidis from the nasopharynx of contacts within the case's network. Contacts with ongoing exposure to the case usually require both chemoprophylaxis and immunoprophylaxis. The exposure risk that arises from playing on a sports team presents some unique challenges in the event a team member becomes diagnosed with IMD. Members of a sports team typically share water bottles, locker room facilities, and travel together; in addition, players may come into direct contact with oral and nasal secretions during the course of play. The purpose of this review was to assess the evidence of the clinical effectiveness and cost-effectiveness of prophylactic treatment for contacts of patients with invasive meningococcal disease (IMD) who are members of sports teams, and to identify and appraise any relevant evidence-based guidelines
Item Description:Title from PDF caption. - "CADTH rapid response service."
Physical Description:1 PDF file (7 pages)