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150223 r ||| eng |
| 020 |
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|a 9780849390005
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| 100 |
1 |
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|a Lo, Donald C.
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| 245 |
0 |
0 |
|a Neurobiology of Huntington's disease
|h Elektronische Ressource
|b applications to drug discovery
|c edited by Donald C. Lo, Robert E. Hughes
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| 260 |
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|a Boca Raton
|b CRC Press/Taylor & Francis Group
|c c2011, 2011
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| 300 |
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|a xx, 312 p.
|b ill
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| 505 |
0 |
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|a Includes bibliographical references and index
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| 505 |
0 |
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|a Huntington's disease : clinical features and routes to therapy / Henry L. Paulson and Roger L. Albin -- Huntington's disease pathogenesis : mechanisms and pathways / Albert R. La Spada, Patrick Weydt, and Victor V. Pineda -- Protein interactions and target discovery in Huntington's disease / John P. Miller and Robert E. Hughes --Target validation for Huntington's disease / Seung P. Kwak, James K.T. Wang, and David S. Howland -- High-throughput and high-content screening for Huntington's disease therapeutics / Hemant Varma, Donald C. Lo, and Brent R. Stockwell -- Value of invertebrate genetics and biology to develop neuroprotective and preventive medicine in Huntington's disease / Christian Neri -- Mouse models for validating preclinical candidates for Huntington's disease / X. William Yang and Michelle Gray -- Pharmaceutical development for Huntington's disease / Richard J. Morse ... [et al.] -- RNA- and DNA-based therapies for Huntington's disease / Meghan Sass and Neil Aronin -- Recombinant intrabodies as molecular tools and potential therapeutics for Huntington's disease / Ali Khoshnan ... [et al.] -- Biomarkers to enable the development of neuroprotective therapies for Huntington's disease / Steven M. Hersch and H. Diana Rosas -- Huntington disease : clinical experimental therapeutics / E. Ray Dorsey and Ira Shoulson
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| 653 |
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|a Drug Discovery / methods
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| 653 |
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|a Huntington Disease / physiopathology
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| 653 |
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|a Huntington Disease / drug therapy
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| 700 |
1 |
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|a Hughes, Robert E.
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| 041 |
0 |
7 |
|a eng
|2 ISO 639-2
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| 989 |
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|b NCBI
|a National Center for Biotechnology Information
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| 490 |
0 |
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|a Frontiers in neuroscience
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| 856 |
4 |
0 |
|u https://www.ncbi.nlm.nih.gov/books/NBK55996
|3 Volltext
|n NLM Bookshelf Books
|3 Volltext
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| 082 |
0 |
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|a 610
|