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|a 030911988X
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|a 9780309119887
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| 100 |
1 |
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|a Olsen, LeighAnne
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| 245 |
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|a Redesigning the clinical effectiveness research paradigm
|h Elektronische Ressource
|b innovation and practice-based approaches : workshop summary
|c LeighAnne Olsen and J. Michael McGinnis, editors ; Institute of Medicine of the National Academies
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| 260 |
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|a Washington, D.C.
|b National Academies Press
|c 2010, c2010
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| 300 |
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|a xxi, 418 p.
|b ill.
|c 23 cm
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| 505 |
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|a Evidence development for healthcare decisions: improving timeliness, reliability, and efficiency -- Cases in point: learning from experience -- Taking advantage of new tools and techniques -- Organizing and improving data utility -- Moving to the next generation of studies -- Aligning policy with research opportunities -- Organizing the research community for change
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| 505 |
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|a Includes bibliographical references
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| 653 |
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|a United States
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| 653 |
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|a Research Design
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| 653 |
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|a Evidence-Based Medicine
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| 653 |
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|a Outcome Assessment, Health Care
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| 653 |
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|a Utilization Review
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| 700 |
1 |
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|a McGinnis, J. Michael
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| 710 |
2 |
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|a Institute of Medicine (U.S.)
|b Roundtable on Value & Science-Driven Health Care
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| 710 |
2 |
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|a National Academies Press (U.S.)
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| 041 |
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|a eng
|2 ISO 639-2
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| 989 |
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|b NCBI
|a National Center for Biotechnology Information
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| 490 |
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|a Learning healthcare system series
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| 856 |
4 |
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|u https://www.ncbi.nlm.nih.gov/books/NBK51016
|3 Volltext
|n NLM Bookshelf Books
|3 Volltext
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| 856 |
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|u http://www.nap.edu/catalog.php?record_id=12197
|3 Volltext
|n Provider site
|3 Volltext
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|a 610
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| 520 |
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|a As part of the Roundtable's Learning Healthcare System series of workshops, clinical researchers, academics, and policy makers gathered for the workshop Redesigning the Clinical Effectiveness Research Paradigm: Innovation and Practice-Based Approaches. Participants explored cutting-edge research designs and methods and discussed strategies for development of a research paradigm to better accommodate the diverse array of emerging data resources, study designs, tools, and techniques. Presentations and discussions are summarized in this volume."--Publisher's description
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| 520 |
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|a In the emerging era of tailored treatments and rapidly evolving practice, ensuring the translation of scientific discovery into improved health outcomes requires a new approach to clinical evaluation. A paradigm that supports a continual learning process about what works best for individual patients will not only take advantage of the rigor of trials, but also incorporate other methods that might bring insights relevant to clinical care and endeavor to match the right method to the question at hand. The Institute of Medicine Roundtable on Value & Science-Driven Health Care's vision for a learning healthcare system, in which evidence is applied and generated as a natural course of care, is premised on the development of a research capacity that is structured to provide timely and accurate evidence relevant to the clinical decisions faced by patients and providers.
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| 520 |
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|a "Recent scientific and technological advances have accelerated our understanding of the causes of disease development and progression, and resulted in innovative treatments and therapies. Ongoing work to elucidate the effects of individual genetic variation on patient outcomes suggests the rapid pace of discovery in the biomedical sciences will only accelerate. However, these advances belie an important and increasing shortfall between the expansion in therapy and treatment options and knowledge about how these interventions might be applied appropriately to individual patients. The impressive gains made in Americans' health over the past decades provide only a preview of what might be possible when data on treatment effects and patient outcomes are systematically captured and used to evaluate their effectiveness. Needed for progress are advances as dramatic as those experienced in biomedicine in our approach to assessing clinical effectiveness.
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