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150202 ||| eng |
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|a 9783319139579
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| 100 |
1 |
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|a Dietel, Manfred
|e [editor]
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| 245 |
0 |
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|a Pre-Analytics of Pathological Specimens in Oncology
|h Elektronische Ressource
|c edited by Manfred Dietel, Christian Wittekind, Gianni Bussolati, Moritz Winterfeld
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| 250 |
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|a 1st ed. 2015
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| 260 |
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|a Cham
|b Springer International Publishing
|c 2015, 2015
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| 300 |
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|a VI, 133 p. 65 illus., 61 illus. in color
|b online resource
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| 505 |
0 |
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|a What Is Pre-Analytics in Surgical Pathology? -- Histologic Validation of Vacuum Sealed Formalin -- Free Tissue Preservation and Transport System -- Pre-Analytics and Molecular Pathology -- Experiences in Vacuum Preparation of Routine Specimens -- Tissue Heterogeneity as a Pre-Analytical Source of Variability -- Vacuum Fixation of Breast Specimens Before Grossing -- How Do Short Fixation and Rapid Microwave Processing Affect Her2 Testing? -- Current Projects in Pre-Analytics – Where to Go? -- Nucleic Acid Extraction from FFPE Tissue as Critical Preanalytic Step for NGS Applications -- Experiences With Pre-Analytics of Lung Specimen -- Experiences With Pre-Analytics of GI-Specimen -- Bone Marrow Work-Up -- Two-Temperature Fixation Preserves Activation Status with High Efficiency -- Towards the Lean Lab. The Industry Challenge.
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| 653 |
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|a Medicine / Research
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| 653 |
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|a Biology / Research
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| 653 |
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|a Biomedical Research
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| 653 |
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|a Oncology
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| 653 |
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|a Pathology
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| 653 |
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|a Surgery
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| 700 |
1 |
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|a Wittekind, Christian
|e [editor]
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| 700 |
1 |
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|a Bussolati, Gianni
|e [editor]
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| 700 |
1 |
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|a Winterfeld, Moritz
|e [editor]
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| 041 |
0 |
7 |
|a eng
|2 ISO 639-2
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| 989 |
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|b Springer
|a Springer eBooks 2005-
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| 490 |
0 |
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|a Recent Results in Cancer Research
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| 028 |
5 |
0 |
|a 10.1007/978-3-319-13957-9
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| 856 |
4 |
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|u https://doi.org/10.1007/978-3-319-13957-9?nosfx=y
|x Verlag
|3 Volltext
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| 082 |
0 |
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|a 616.994
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| 520 |
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|a This book presents an overview of the most important current developments in the pre-analytical handling of tissue. It addresses in particular potential ways to improve the situation whereby methods employed in the pre-analytical phase – the period from surgical removal of tissue to the start of pathological processing – have remained essentially unchanged for decades with only modest standardization. It is examined how the pre-analytical period can be optimized, resulting not only in an increase in diagnostic quality but also in a reduction in processing time and costs. Among the key topics examined are the so-called cold ischemia time between tissue removal and fixation, the potential superiority of vacuum-based preservation over immediate formalin fixation, two-temperature fixation, molecular analysis methods, and the pre-analytics of specimens from particular tissues. Readers will find this book to be an important update that reveals the full importance of the pre-analytical phase for quality of pathological work-up
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