In Vitro Toxicology Systems

In Vitro Toxicology Systems brings together important issues and considerations needed in order to develop a workable, reliable, integrated testing strategy for the replacement of animals in toxicity testing regimes. This thorough volume includes sections on in vitro models for systemic organ toxici...

Full description

Bibliographic Details
Other Authors: Bal-Price, Anna (Editor), Jennings, Paul (Editor)
Format: eBook
Language:English
Published: New York, NY Humana 2014, 2014
Edition:1st ed. 2014
Series:Methods in Pharmacology and Toxicology
Subjects:
Online Access:
Collection: Springer eBooks 2005- - Collection details see MPG.ReNa
Table of Contents:
  • The Past, Present and Future of Chemical Risk Assessment.- In Vitro Systems for Hepatotoxicity Testing
  • In Vitro Methods for Cardiotoxicity Testing
  • Renal Cell Culture
  • Cellular Models for In Vitro Lung Toxicology
  • In Vitro Developmental Neurotoxicity Testing: Relevant Models and Endpoints
  • Blood Brain Barrier In Vitro Models and Their Applications in Toxicology
  • Ocular Toxicity
  • In Vitro Models for Ototoxic Research
  • Dermal Toxicity: Skin Sensitization
  • Immunotoxicity
  • Reproductive Toxicity
  • Evaluating Endocrine Disruption In Vitro
  • Current and Emerging In Vitro Methods for Genotoxicity and Carcinogenicity
  • Use of Induced Pluripotent Stem Cells in Drug Toxicity Screening
  • Human Stem/Progenitor Cell-Based Assays for Neurodevelopmental Toxicity Testing
  • High Content Imaging Approaches for In Vitro Toxicology
  • Application of Omics Technologies to In Vitro Toxicology
  • Stress Response Pathways
  • Translational Biomarkers, In Vitro and In Vivo
  • Nanotoxicology
  • Consideration of Metabolism in In Vitro Cellular Systems
  • In Vitro Approaches to Predictive Biokinetics
  • Extrapolating In Vitro Results to Predict Human Toxicity
  • Considerations in the Development of In Vitro Toxicity Testing Methods Intended for Regulatory Use