Clinical Nephrotoxins Renal Injury from Drugs and Chemicals

GEORGE A. PORTER information is an international commodity whose The field of clinical nephrotoxicity involves toxins of interpretation and application are strongly influenced diverse origin and exposure. A significant contribution by both the cultural and ethnic background of the to this problem ar...

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Bibliographic Details
Other Authors: de Broe, Marc E. (Editor), Porter, George A. (Editor), Bennett, William M. (Editor), Verpooten, G.A. (Editor)
Format: eBook
Language:English
Published: Dordrecht Springer Netherlands 1998, 1998
Edition:1st ed. 1998
Subjects:
Online Access:
Collection: Springer Book Archives -2004 - Collection details see MPG.ReNa
Table of Contents:
  • A. General
  • 1. Clinical relevance
  • 2. Renal handling of drugs and xenobiotics
  • 3. Immunologically-mediated toxin-induced renal diseases
  • 4. Cellular mechanisms of nephrotoxity
  • 5. Experimental models
  • B. Specific Drugs
  • Introduction: Anti-infectious agents
  • 6. Aminoglycosides and vancomycin
  • 7. The renal toxicity of beta-lactam antibiotics: Mechanisms and clinical implications
  • 8. Amphotericin B
  • 9. Miscellaneous drugs with nephrotoxic potential
  • 10. Antiviral agents
  • Introduction: Analgesic related renal injury
  • 11. Analgesics
  • 12. Nonsteroidal anti-inflammatory drugs: Effects on kidney function
  • 13. 5-Aminosalicyclic acid and chronic interstitial nephritis
  • 14. Nephrotoxicity of gold salts, D-penicillamine, and allopurinol
  • 15. Renal injury from angiotensin I converting enzyme inhibitors
  • 16. Diuretics
  • 17. Anticancer: Cisplatin/carboplatin
  • Introduction: Immunosuppressive drugs
  • 18. Cyclosporine/tacrolimus (FK-506)
  • 19. OKT3 Nephrotoxicity: From acute tubular necrosis to hemolytic uremic syndrome
  • 20. Cytokine associated renal dysfunction: Interleukins and interferons
  • 21. Contrast associated nephropathy: Presentation, pathophysiology and management
  • Introduction: Environmental nephrotoxins
  • 22. Lead nephropathy
  • 23. Cadmium-induced renal effects in the general environment
  • 24. Mercury
  • 25. Role of environmental/occupational exposure to organic solvents, silicon-containing compounds and pesticides in the development and progression of renal disease
  • 26. Lithium and the kidney
  • 27. Renal disease associated with illicit drug abuse
  • 28. Renal toxicity of anesthetic agents
  • 29. Nephrotoxicity of herbal remedies and trace elements used as food additives
  • 30. Balkan nephropathy
  • C. Prevention
  • 31. Urinary biomarkers and nephrotoxicity.-32. Principles of drug dosing in renal failure
  • 33. Practical dosing