Leukotrienes New Concepts and Targets for Therapy

In the two decades since the elusive "slow reacting substance of anaphylaxis" (SRS-A) was identified as a product of the action of the 5-lipoxygenase enzyme on arachidonic acid, it has been well established that the leukotrienes are key mediators of both alIergy and inflammation. Their rel...

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Bibliographic Details
Other Authors: Rodger, Ian (Editor), Botting, Jack H. (Editor), Dahlén, Sven-Erik (Editor)
Format: eBook
Language:English
Published: Dordrecht Springer Netherlands 1998, 1998
Edition:1st ed. 1998
Subjects:
Online Access:
Collection: Springer Book Archives -2004 - Collection details see MPG.ReNa
Table of Contents:
  • 1 Molecular mechanisms of leukotriene synthesis: the changing paradigm
  • 2 Leukotriene receptors
  • 3 Enzymes involved in the production of leukotrienes and related molecules
  • 4 Cysteinyl-leukotriene receptors and transduction mechanisms in airway cells
  • 5 How to measure leukotrienes in man
  • 6 Influence of leukotrienes and anti-leukotrienes on airway tone and migration of inflammatory cells
  • 7 Leukotrienes in airways obstruction and inflammation evoked by allergen
  • 8 Leukotrienes in induced airway obstruction
  • 9 Role of leukotrienes in aspirin-induced asthma
  • 10 How to use anti-leukotrienes in the treatment of asthma
  • 11 Transcription factors HSF and HF-?B as targets for cytoprotective eicosanoids: a new strategy for therapeutic intervention
  • 12 Vascular biology of the leukotrienes
  • 13 Leukotrienes in cardiovascular disease
  • 14 Leukotriene B4: agonist for the fat regulator PPAR?
  • 15 The role of leukotrienes in rhinitis