Structure-Activity Relationships of Anti-Tumour Agents

The Workshop series of the "Koningin Wilhelmina Fonds" is a feature of the interest of this Foundation to promote research and education in the field of cancer, aiming to improve prognosis of the cancer patient. For almost a century, surgery has now been the main treatment modality for the...

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Bibliographic Details
Other Authors: Reinhoudt, D.N. (Editor), Connors, T.A. (Editor), Pinedo, H.M. (Editor), van de Poll, K.W. (Editor)
Format: eBook
Language:English
Published: Dordrecht Springer Netherlands 1983, 1983
Edition:1st ed. 1983
Series:Developments in Pharmacology
Subjects:
Online Access:
Collection: Springer Book Archives -2004 - Collection details see MPG.ReNa
Table of Contents:
  • 1. Introduction
  • 2. Strategy for the Discovery and Development of Novel Anticancer Agents
  • 3. Quantitative Structure-Activity Relationship Studies Around Cytotoxic Drugs
  • 4. Alkylating Prodrugs in Cancer Chemotherapy
  • 5. Structure-Activity Relationships for Anti-Tumour Platinum Complexes
  • 6. Bioreductive Alkylation — Naturally Occurring Quinones as Potential Candidates
  • 7. Structure-Activity Relationships in Doxorubicin Related Compounds
  • 8. Structure-Activity Relationships Among Antitumour Quinones
  • 9. In Vitro Oxidative Activation: A Model for the Cytotoxic Action of 9-Hydroxy Ellipticine Derivatives
  • 10. DTIC: A Springboard to New Antitumour Agents
  • 11. Nitrosoureas
  • 12. Oxazaphosphorine Cytostatics: Structure-Activity Relationships, Selectivity and Metabolism, Regional Detoxification
  • 13. Studies on Antitumour Antibiotics, Low Molecular Weight Immuno-Modifiers and Their Analogs and Derivatives