The Search for New Anticancer Drugs
Most of the anti-cancer drugs in use today were discovered by happy accident rather than design, yet the rational design of better anti-cancer drugs remains a cherished goal, and one of the most important challenges facing medical science. This book represents a compilation of views and progress rep...
| Other Authors: | , |
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| Format: | eBook |
| Language: | English |
| Published: |
Dordrecht
Springer Netherlands
1992, 1992
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| Edition: | 1st ed. 1992 |
| Series: | Cancer Biology and Medicine
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| Subjects: | |
| Online Access: | |
| Collection: | Springer Book Archives -2004 - Collection details see MPG.ReNa |
Table of Contents:
- 1. Is there a future for the small molecule in developmental cancer chemotherapy?
- 2. The role of medicinal chemistry in the discovery of DNA-active anticancer drugs: from random searching, through lead development, to de novo design
- 3. In vitro systems for anticancer drug testing
- 4. Tumour hypoxia: challenges for cancer chemotherapy
- 5. Computer modelling and drug design
- 6. Differentiation inducers and their potential use in the treatment of acute myelogenous leukaemia
- 7. Angiosuppression
- 8. Preclinical evaluation and phase I trials
- 9. Evaluation: how should a new treatment be evaluated?
- 10. Oncogene-targeted antisense oligonucleotides: tools for genetic analysis or new anticancer drugs?