Biological Models in Radiopharmaceutical Development
Radiophannaceuticals labeled with short-lived radionuclides are utilized to unravel biochemical processes, and to diagnosis and treat diseases of the living body are-developed through extensive evaluation in ~iological models. 'fhC first attempt to compile information was a volume entitled ANIM...
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| Format: | eBook |
| Language: | English |
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Dordrecht
Springer Netherlands
1996, 1996
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| Edition: | 1st ed. 1996 |
| Series: | Developments in Nuclear Medicine
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| Subjects: | |
| Online Access: | |
| Collection: | Springer Book Archives -2004 - Collection details see MPG.ReNa |
Table of Contents:
- Preface
- Acknowledgements
- Scope of the Work
- Guidelines for Research with Animals
- Moral and Ethical Considerations
- Principles and Training Programs
- Design of Candidate Radiopharmaceuticals
- Identification of Clinical Need
- Choice of Radionuclide
- Screening Studies
- Drug Development
- Concept of Biological Model
- In Vitro Models
- Choice of Biological Models
- Species Variations
- Transgenic Mice
- Dogs and Kangaroos
- Poison Arrow Frog
- Giraffe
- Tomographic Phisiological Chemistry
- ARG
- SPET
- PET
- SIMS
- Keyword Guide to Selection of Biological Models
- References
- Glossary of Abbreviations