The Meaning of Nucleocytoplasmic Transport

The means by which proteins and RNAs are exchanged between cytoplasm and nucleus have interested cell biologists for many years, and the field has seen a number of exciting recent advances. Much has been learned about the intricate architecture of the nuclear pore-complex, the mechanisms by which tr...

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Bibliographic Details
Main Authors: Agutter, Paul S., Taylor, Philip L. (Author)
Format: eBook
Language:English
Published: Berlin, Heidelberg Springer Berlin Heidelberg 1996, 1996
Edition:1st ed. 1996
Series:Molecular Biology Intelligence Unit
Subjects:
Online Access:
Collection: Springer Book Archives -2004 - Collection details see MPG.ReNa
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505 0 |a 1. Perspectives in Transport -- 2. The Vagaries of Diffusion -- 3. Cellular Structures and Nucleocytoplasmic Transport -- 4. Events at the Pore-Complex -- 5. Events Involving the Nucleoskeleton and Cytoskeleton -- 6. Regulation and Pathologies of Nucleocytoplasmic Transport -- 7. Evaluation of a Model 
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520 |a The means by which proteins and RNAs are exchanged between cytoplasm and nucleus have interested cell biologists for many years, and the field has seen a number of exciting recent advances. Much has been learned about the intricate architecture of the nuclear pore-complex, the mechanisms by which transport substrates are sorted, and the supply of energy for exchange processes. This book attempts a general review of the growing body of knowledge. However, the authors challenge the presumptions implicit in some interpretations of the evidence, re-examining the concept of "transport" within cells, and suggesting that lessons learned from nucleocytoplasmic transport studies can elucidate wider aspects of cell biology