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Borna Disease

Borna disease was first described over 200 years ago, in what is now Southeastern Germany, as a fatal neurologic affliction of horses and was considered a curiosity for many decades. The causative agent was unknown, and the animal species infected in nature were limited to horses and sheep. Today, a...

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Bibliographic Details
Other Authors: Koprowski, Hilary (Editor), Lipkin, W. Ian (Editor)
Format: eBook
Language:English
Published: Berlin, Heidelberg Springer Berlin Heidelberg 1995, 1995
Edition:1st ed. 1995
Series:Current Topics in Microbiology and Immunology
Subjects:
Virology
Neurology 
Neurology
Immunology
Pathology
Online Access:
Collection: Springer Book Archives -2004 - Collection details see MPG.ReNa
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505 0 |a List of Contents -- Molecular Biology of Borna Disease Virus -- Natural and Experimental Borna Disease in Animals -- A Borna-Like Disease of Ostriches in Israel -- Borna Disease—Neuropathology and Pathogenesis -- Immunopathogenesis of Borna Disease -- Behavioral Disturbances and Pharmacology of Borna Disease -- Human Infections with Borna Disease Virus and Potential Pathogenic Implications 
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520 |a Borna disease was first described over 200 years ago, in what is now Southeastern Germany, as a fatal neurologic affliction of horses and was considered a curiosity for many decades. The causative agent was unknown, and the animal species infected in nature were limited to horses and sheep. Today, as described in this volume, the host range has extended to all warm-blooded animals, the genes and proteins of the virus have been identified, and many of the mechanisms responsible for behavioral disturbances are understood. Serologic studies suggest that BDV or related agents are likely to play a role in human neuropsychiatric diseases 

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