Clinical Pharmacology in Psychiatry Strategies in Psychotropic Drug Development

This book contains the papers from invited lecturers as well as selected contributions presented at the 6th International Meeting on Clinical Pharmacology in Psychiatry (I.M.C.P.P.) held in Geneva, Switzerland, 5-7 June 1991. At this meeting the basic theme of the previous meetings in this series (C...

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Bibliographic Details
Other Authors: Gram, Lars F. (Editor), Balant, Luc P. (Editor), Meltzer, Herbert Y. (Editor), Dahl, Svein G. (Editor)
Format: eBook
Language:English
Published: Berlin, Heidelberg Springer Berlin Heidelberg 1993, 1993
Edition:1st ed. 1993
Series:Psychopharmacology Series
Subjects:
Online Access:
Collection: Springer Book Archives -2004 - Collection details see MPG.ReNa
Table of Contents:
  • Molecular Modeling of Neurotransmitter Receptors
  • Structure-Function Analysis of the Three ?-Adrenergic Catecholamine Receptors
  • Serotonin Receptor Subtypes
  • Developmental Regulation of 5-HT2 and 5-HT1c Receptor Gene Expression in Rat Brain
  • Relevance of 5-HT Autoreceptors for Psychotropic Drug Action
  • Brain Serotonin Subsystem Complexity and Receptor Heterogeneity: Therapeutic Potential of Selective Serotonin Agonists and Antagonists
  • Serotonin Receptors and Antipsychotic Drug Action
  • The Third Dopamine Receptor (D3): New Perspectives in Therapeutics
  • PET Examination of Central D2 Dopamine Receptor Occupancy in Relation to Extrapyramidal Syndromes in Patients Being Treated with Neuroleptic Drugs
  • Dopaminergic and Serotonergic Aspects of Acute Extrapyramidal Syndromes
  • Methods to Facilitate Early Exploratory Testing of Novel Psychopharmacologic Agents in Humans
  • Neuroleptics and Diagnostic Heterogeneity in Relation to Drug Evaluation
  • Residual and Negative Symptoms in Treatment with Neuroleptics
  • Clinical Dosing of Neuroleptics
  • Diagnostic Heterogeneity in Relation to Drug Evaluation: Antidepressants
  • Dose-Effect Relationships for Tricyclic Antidepressants: The Basis for Rational Clinical Testing of New Antidepressants
  • Dose-Effect and Concentration-Effect Relationships with New Antidepressants
  • Therapeutic Potentials of Recently Introduced Antidepressants
  • Role of Genetic Polymorphism in Psychopharmacology — An Update
  • Psychotropic Drug Metabolism and Clinical Monitoring
  • Disposition of the Neuroleptics Perphenazine, Zuclopenthixol, and Haloperidol Cosegregates with Polymorphic Debrisoquine Hydroxylation
  • Phenotypes for Psychotropic Drug Metabolism in the Elderly
  • Analysis of 935 Haloperidol Concentration Measurements Obtained During RoutineDrug Monitoring of 134 Patients
  • Power Analysis for Correlation of Plasma Level and Clinical Data