Prostaglandins and Leukotrienes in Gastrointestinal Diseases

In OCtober 1986, recognized authorities from a variety of disciplines met in Lisbon, Portugal, to review recent knowledge on eicosanoids - i. e., prostaglandins, throm­ boxane A , and leukotrienes - and their role in gastrointestinal diseases. 2 Briefly, in the stomach endogenous as well as exogenou...

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Bibliographic Details
Other Authors: Domschke, W. (Editor), Dammann, H.G. (Editor)
Format: eBook
Language:English
Published: Berlin, Heidelberg Springer Berlin Heidelberg 1988, 1988
Edition:1st ed. 1988
Subjects:
Online Access:
Collection: Springer Book Archives -2004 - Collection details see MPG.ReNa
Table of Contents:
  • Biology and Pharmacology of Prostaglandins and Leukotrienes
  • Biosynthesis and Metabolism of Prostaglandins and Thromboxanes. Quantitative Determination in Biological Material
  • Discussion
  • Involvement of the Eicosanoids, Thromboxane A2 and Leukotriene C4 in Gastric Mucosal Damage
  • Discussion
  • Microvascular Injury and the Role of Leukotrienes and Prostaglandins in Acute Mucosal Damage and Protection
  • Discussion
  • Inhibition of Prostaglandin Synthesis and Proliferation of the Gastric Mucosa
  • Discussion
  • Role of Prostaglandins in Intestinal Fluid Secretion
  • Discussion
  • Novel Leukotriene D4 Receptor Antagonists and 5-Lipoxygenase Inhibitors: Implications in Human Disease
  • Discussion
  • Protective Effects on the Gastrointestinal Mucosa. New Aspects of the Last two Years
  • “Aggressive” and “Protective” Factors in the Pathogenesis of Peptic Ulcer Disease
  • Discussion
  • Heartburn and Mucosal Barrier Weakness
  • Discussion
  • Discussion
  • Colitis and Non-Steroidal Anti-Inflammatory Drugs
  • Discussion
  • Therapeutic Role for Prostaglandins in Ulcerative Colitis?
  • Discussion
  • Inflammatory Bowel Disease: Treatment Modalities and Mucosal Prostaglandin/Leukotriene Formation
  • Discussion
  • Prostaglandins: Their Potential Therapeutic Value in the Upper Gastrointestinal Tract
  • The Natural History of Ulcer Disease and its Impact upon Therapeutic Options and Assessment of Drug Safety
  • Benefits and Risks of Long-Term Medical Therapy with Histamine H2-Receptor Antagonists in Ulcer Disease — A Physician’s View
  • Benefits and Risks of Long-Term Medical Therapy with Histamine H2-Receptor Antagonists in Ulcer Disease: A Surgeon’s View
  • The Surgical Approach to Ulcer Disease and its Complications — Hasthere been a Change in the Last Decade?
  • The Efficacy of Prostaglandins in the Prevention of Stress Lesions in the Critically I11 Patient
  • Discussion Following this Section
  • Clinical Aspects of the Protective Effects of Prostaglandins on Non-Steroidal Anti-Inflammatory Drug-Associated Mucosal Injury
  • Discussion
  • Prostaglandins and Leukotrienes in Gastrointestinal Diseases — Present Clinical Role
  • Gastrointestinal Microbleeding and Ulcerogenic Drugs: Prevention by Co-Administration of Prostaglandins
  • Discussion
  • Exogenous Prostaglandins and Their Analogues in Gastric Ulcer Therapy
  • Exogenous Prostaglandins and Their Analogues in Duodenal Ulcer Therapy
  • Discussion
  • Clinical Safety of Antiulcer Prostaglandins: An Overview
  • Discussion
  • Ulcer Healing Drugs and Endogenous Prostaglandins: Carbenoxolone, Antacids, Sucralfate, Bismuth, and H2-Receptor Antagonists
  • Discussion
  • Smoking and Ulcer Healing — Role for Prostaglandins?
  • Discussion
  • Ulcer Healing by Prostaglandins — Due to Decreased Acidity or Enhanced Mucosal Defense?
  • Discussion
  • Diarrheagenic Syndromes Sensitive to Prostaglandin Synthetase Inhibitors
  • The Functional Role of Prostanoids in the Gastroduodenal Mucosa
  • Role of Leukotrienes in Gastric Mucosal Damage and Protection
  • Discussion
  • Effect of Prostaglandins on the Motility of the Digestive Tract
  • Discussion
  • Gastroduodenal Bicarbonate Secretion in Mucosal Protection
  • Discussion
  • Prostaglandins and Cellular Restitution — Physiological and Pathological Implications
  • Discussion
  • Prostanoid Inhibition of Acid Secretion — Cellular Mechanisms in Canine Fundic Mucosa
  • Discussion
  • The Protective Effects of Prostaglandins on the Gastric Microvasculature
  • Non-Steroidal Anti-Inflammatory Drugs and Peptic Ulcer
  • Discussion
  • Mechanism of Injury to Gastric Mucosa by Non-Steroidal Anti-Inflammatory Drugs and the Protective Role of Prostaglandins
  • Discussion
  • Can Nonantisecretory Doses of Prostaglandins Prevent Mucosal Damage inNon-Steroidal Anti-Inflammatory Drugs?