Control of Immune Response by Endocrine Factors Malaria Vaccine Controlled Drug Delivery Enzyme-Immunoassay

Malaria is a disease of long duration and chronicity. Typical infections with Plas­ modium vivax or P. ovale last 2 to 3 years, with periodic remissions and relapses. P. malariae may persist as a latent inapparent infection up to 50 years. Even with P. Jalciparum, the most highly pathogenic species...

Full description

Bibliographic Details
Corporate Author: SpringerLink (Online service)
Format: eBook
Language:English
Published: Berlin, Heidelberg Springer Berlin Heidelberg 1987, 1987
Edition:1st ed. 1987
Series:Progress in Clinical Biochemistry and Medicine
Subjects:
Online Access:
Collection: Springer Book Archives -2004 - Collection details see MPG.ReNa
LEADER 02680nmm a2200277 u 4500
001 EB000671240
003 EBX01000000000000000524322
005 00000000000000.0
007 cr|||||||||||||||||||||
008 140122 ||| eng
020 |a 9783642715020 
245 0 0 |a Control of Immune Response by Endocrine Factors Malaria Vaccine Controlled Drug Delivery Enzyme-Immunoassay  |h Elektronische Ressource 
250 |a 1st ed. 1987 
260 |a Berlin, Heidelberg  |b Springer Berlin Heidelberg  |c 1987, 1987 
300 |a 146 p  |b online resource 
505 0 |a The Control of Immune Response by Endocrine Factors and the Clinical Significance of Such Regulation -- Malaria Vaccine -- Controlled Drug Delivery -- Enzyme-Immunoassay: A Review -- Author Index Volumes 1–4 
653 |a Biochemistry 
653 |a Anthropology 
710 2 |a SpringerLink (Online service) 
041 0 7 |a eng  |2 ISO 639-2 
989 |b SBA  |a Springer Book Archives -2004 
490 0 |a Progress in Clinical Biochemistry and Medicine 
028 5 0 |a 10.1007/978-3-642-71502-0 
856 4 0 |u https://doi.org/10.1007/978-3-642-71502-0?nosfx=y  |x Verlag  |3 Volltext 
082 0 |a 572 
520 |a Malaria is a disease of long duration and chronicity. Typical infections with Plas­ modium vivax or P. ovale last 2 to 3 years, with periodic remissions and relapses. P. malariae may persist as a latent inapparent infection up to 50 years. Even with P. Jalciparum, the most highly pathogenic species of human malaria, immunity de­ velops only slowly l). Under natural conditions in a holoendemic region where expo­ sure to reinfection is frequent and sustained, children that survive their initial infec­ tions show an enlarged spleen and are likely to continue to show parasites until puber­ ty, or even beyond. In such a region adults do not have a markedly enlarged spleen, rarely show parasites and are rarely ill with malaria. This acquired immunity is effec­ tive mainly against the local strains of falciparum malaria and fades rapidly if the individual lives for some months in a non-malarious region. Nevertheless, if such an immunity could be induced earlier by vaccination, and especially if it could be induced in young children, many lives would be saved and much illness prevented. An effective vaccine would also serve as an additional tool which, combined with mosquito control measures and appropriate chemotherapy, might greatly reduce the incidence of malaria. Clearly a vaccine could also be useful for the protection of short term visitors to malarious regions. Such protection is becoming increasingly difficult to provide as drugresistant strains of P. Jalciparum continue to spread 2)