HLA Class II Antigens A Comprehensive Review of Structure and Function

This volume deals with the structure and function of molecules that have, during the last decade, turned out to have a central role in immune responses. Trans­ plantation antigens were discovered and characterized by Gorer about 50 years ago, and the biological basis for the unequalled complexity of...

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Bibliographic Details
Other Authors: Solheim, Bjarte G. (Editor), Moller, Erna (Editor), Ferrone, Soldano (Editor)
Format: eBook
Language:English
Published: Berlin, Heidelberg Springer Berlin Heidelberg 1986, 1986
Edition:1st ed. 1986
Subjects:
Online Access:
Collection: Springer Book Archives -2004 - Collection details see MPG.ReNa
Table of Contents:
  • Class II Antigens: T Cells
  • Class II MHC Antigens and Hematopoiesis
  • Class II MHC Antigens and Erythropoiesis
  • Expression of Class II Antigens on Nonhematopoietic Tumor Cells
  • Class II HLA Antigens in Benign and Malignant Lesions of Melanocytic Origin
  • Molecular Genetics
  • Molecular Polymorphism of Human Immune-Response-Genes
  • Molecular Genetics as a Tool in Clinical Transplantation
  • Biological Implications
  • The Role of Human Class II Molecules in Activation of T4 Lymphocytes
  • Class II HLA Antigens in Autoimmune and Immune-Mediated Diseases
  • The Role of HLA Class II Antigens in Clinical Transplantation
  • Relevance of HLA-D/-DR Matching in a National Kidney Transplant Program
  • The Pig as a Model to Assess the Effect of Class II MHC Antigen Matching on Renal Allograft Survival
  • Preparation, Characterization and Utilization of Monoclonal Antibodies to the Gene Products of the HLA-D Region, with Special Emphasis on those to Polymorphic Determinants
  • Cellular Detection
  • Cellular Detection of HLA Class II-Encoded Determinants: Subtype Polymorphims of HLA-D
  • Cellular Detection of Human Class II MHC Antigens by Alloreactive T Cell Clones
  • Cellular Detection of Human Class II Antigens: Delineation of a Novel HLA-DP-like Suppressor Restriction System DY, the Sequential Expression of Class II Antigens, and a Pronounced Functional Flexibility of Class II Alloproliferate T Cell Clones
  • Regulation and Expression
  • Modulation of Class II Antigens by Interferons
  • Changing Antigenic Profiles of HLA Class II Antigens on Activated T Cells and Their Biological Effects
  • Tissue Distribution of Class II Transplantation Antigens: Presence on Normal Cells
  • Class II MHC Antigens on Human Monocytes, Endothelial Cells, and Dendritic Cells
  • Molecular Biology
  • Genes and Antigens of the HLA-D Region
  • Physiologic Regulation of Class II Major Histocompatibility Complex Gene Expression
  • Epitopes Are the Functional Units of HLA Class II Molecules and Form the Molecular Basis for Disease Susceptibility
  • Biochemistry
  • Structure of Human Class II Antigens Expressed by a Homozygous Lymphoblastoid B Cell Line
  • The Complexity of HLA-DQ Molecules
  • HLA-DP: Current Status
  • Genes Encoding Mouse Ia
  • Structural and Functional Studies of Mouse Class II Genes
  • Cross-reaction Between Various Species
  • Cross-reactions of Class II Histocompatibility Antigens of Various Species
  • Differences Between Ethnic Groups
  • Human Class II Antigen in Different Ethnic Groups
  • Serological Definition
  • Serology of HLA Class II Antigens: Methodological Aspects
  • Alloantisera Against Human Class II Antigens: Definition and Methodology
  • Monoclonal Antibodies Against HLA Class II Antigens