Late Sequelae in Oncology

Increasing survival figures and the use of more intense combined treatment regimens in modern oncology have raised the problem of late therapeutic sequelae in long-term survivors after cancer. Recent scientific approaches to late sequelae concentrate on the evaluation of subclinical changes with sop...

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Bibliographic Details
Other Authors: Dunst, Jürgen (Editor), Sauer, Rolf (Editor)
Format: eBook
Language:English
Published: Berlin, Heidelberg Springer Berlin Heidelberg 1995, 1995
Edition:1st ed. 1995
Series:Radiation Oncology
Subjects:
Online Access:
Collection: Springer Book Archives -2004 - Collection details see MPG.ReNa
Table of Contents:
  • 1 Individual Variation of Radio- and Chemosensitivity
  • 1.1 Impact of Endogenous and Exogenous Factors on Radiation Sequelae
  • 1.2 Endogenous and Exogenous Factors Modifying Chemosensitivity to Cytostatic Drugs
  • 2 Neurotoxicity
  • 2.1 Radiation-Induced Injury of the Central Nervous System
  • 2.2 Cytostatic-Induced Central Nervous System Abnormalities
  • 2.3 Radiation Myelopathy
  • 2.4 Acute and Late Toxicity on Peripheral Nerves After Radiotherapy
  • 2.5 Acute and Late Toxicity on Peripheral Nerves After Chemotherapy — A Review
  • 2.6 Endocrine Dysfunction After Brain Tumor Therapy in Children
  • 2.7 Endocrine Dysfunction in Adults After Radiotherapy for Pituitary Adenomas and Suprasellar Tumors
  • 2.8 Late Sequelae Affecting the Ear
  • 2.9 Ototoxicity in Pediatric Oncology
  • 3 Skin and Mucosal Toxicity
  • 3.1 Biological Basis for Skin and Mucosal Toxicity
  • 3.2 Radiation-Induced Fibrosis: Experimental Studies
  • 3.3 Lymphedema of the Arm After Treatment of Breast Cancer
  • 6.1 Nephrotoxicity of Ifosfamide in Children
  • 6.2 Radiation Nephritis
  • 7 Gonadal Toxicity
  • 7.1 Long-Term Gonadal Dysfunction and Its Impact on Bone Mineralization in Patients Following COPP/ABVD Chemotherapy for Hodgkin’s Disease
  • 7.2 Gonadal Dysfunction After Radiotherapy
  • 8 Disturbances of Sceletal Growth
  • 8.1 Dose-Time Considerations for Skeletal Growth Disturbances After Radiotherapy
  • 8.2 Disturbances in Growth of Bone, Muscle, and Fat Tissue Following Irradiation in Childhood
  • 8.3 Growth Failure Secondary to Radiotherapy of Brain Tumors in Childhood
  • 9 Cancerogenesis
  • 9.1 Experiments on the Carcinogenic Potential of Antineoplastic Agents
  • 9.2 Secondary Malignancies Following Cytotoxic Chemotherapy
  • 9.3 Secondary Malignancies After Radiotherapy
  • List of Contributors
  • 3.4 Skin and Mucosal Damage After Radiotherapy for Head and Neck Tumors
  • 3.5 Mucosal Toxicity After Radiochemotherapy
  • 3.6 Complications of the Small Intestine and the Pancreas After Intraoperative Radiotherapy
  • 3.7 Skin Toxicity
  • 4 Lung Toxicity
  • 4.1 Radiation Pneumopathy — Experimental and Clinical Data
  • 4.2 Lung Toxicity of Chemotherapeutic Agents
  • 4.3 Differential Diagnosis of Treatment Sequelae in the Lung
  • 5 Cardiotoxicity
  • 5.1 Evaluation of Late Cardiotoxicity by Pulsed Doppler Echocardiography in Patients Treated for Hodgkin’s Disease
  • 5.2 Anthracycline-Induced Cardiotoxicity in Children: Pathophysiology and Prevention
  • 5.3 Radiation-Induced Cardiotoxicity: Experimental Data
  • 5.4 Cardiotoxicity After Megavoltage Irradiation and Chemotherapy for Hodgkin’s Disease with Special Emphasis on Coronary Heart Disease Mortality — The Freiburg Experience 1940-1992
  • 5.5 Cardiac Morbidity and Mortality Followig Radiotherapy
  • 6 Nephrotoxicity