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140122 ||| eng |
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|a 9781592597055
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| 100 |
1 |
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|a Wu-Pong, Susanna
|e [editor]
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| 245 |
0 |
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|a Biopharmaceutical Drug Design and Development
|h Elektronische Ressource
|c edited by Susanna Wu-Pong
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| 250 |
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|a 1st ed. 1999
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| 260 |
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|a Totowa, NJ
|b Humana Press
|c 1999, 1999
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| 300 |
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|a XII, 436 p
|b online resource
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| 505 |
0 |
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|a 1. An Overview of Biotechnology -- 2. Basic Elements of Molecular Biology -- 3. Tools for Molecular Analysis -- 4. Treatment Options -- 5. Viral Vectors for Gene Therapy -- 6. Nonviral Gene Delivery -- 7. Oligonucleotides and Ribozymes -- 8. Design and Engineering of Proteins as Therapeutic Agents -- 9. Challenges and Issues in the Development of Formulations of Protein Pharmaceuticals -- 10. Protein Drug Delivery -- 11. Protein Drug Manufacturing -- 12. Antibodies -- 13. Immunotherapy -- 14. Product Development and New Drug Approval -- 15. Therapeutic Use of Recombinant Proteins
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| 653 |
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|a Molecular Medicine
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| 653 |
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|a Molecular biology
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| 653 |
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|a Pharmacy
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| 653 |
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|a Pharmacy
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| 653 |
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|a Pharmacology
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| 653 |
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|a Pharmacology/Toxicology
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| 041 |
0 |
7 |
|a eng
|2 ISO 639-2
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| 989 |
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|b SBA
|a Springer Book Archives -2004
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| 856 |
4 |
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|u https://doi.org/10.1007/978-1-59259-705-5?nosfx=y
|x Verlag
|3 Volltext
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| 082 |
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|a 615
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| 520 |
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|a In Biopharmaceutical Drug Design and Development, leading authorities comprehensively review the rapidly increasing array of biopharmaceuticals derived from the molecular biological approaches now so widely available. Designed as an introduction for the novice-or even the professional already acquainted with molecular therapeutics-who wishes to become familiar with both the basics and range of biopharmaceutical initiatives now underway, this informative book illuminates and explains macromolecular and biological drug design, as well as the development, delivery, clinical trials, and government regulation of the new therapeutics. Its eminently practical approach takes the reader from basic biotechnology, through drug conception and design, to state-of-the-art clinical application of both investigational and currently approved biologicals. Topics include fundamental concepts and methods, the applications of biotechnology in medicine and biopharmaceuticals, the drug approval process, and biological product testing. Biopharmaceutical Drug Design and Development provides a detailed description of the state-of-the-art in the generation of today's therapeutics. Its comprehensive coverage will help all medicinal chemists, molecular modelers, pharmacologists, pharmaceutical scientists, and clinical scientists involved in pharmaceutical biotechnology to more deeply understand both the enormous potential of this technology and how best to develop the new therapeutic agents that lie so close ahead
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