Biology of Brain Dysfunction Volume 1

The growth of neurochemistry, molecular biology, and biochemical genetics has led to a burgeoning of new information relevant to the pathogenesis of brain dysfunction. This explosion of exciting new information is crying out for collation and meaningful synthesis. In its totality, it defies systemat...

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Bibliographic Details
Main Author: Gaull, Gerald E.
Format: eBook
Language:English
Published: New York, NY Springer US 1973, 1973
Edition:1st ed. 1973
Subjects:
Online Access:
Collection: Springer Book Archives -2004 - Collection details see MPG.ReNa
Table of Contents:
  • II. Biochemical Roles of Coenzyme Forms of Folic Acid and Vitamin B12
  • III. Central Nervous System Damage Due to Folic Acid Deficiency
  • IV. Central Nervous System Damage Due to Vitamin B12 Deficiency
  • References
  • VII. Prenatal Diagnosis of Chromosomal Abnormalities
  • VIII. Concluding Remarks
  • References
  • 4 Disorders of Glucose Metabolism in Brain Dysfunction
  • I. Introduction
  • II. Systemic Disorders of Glucose Metabolism
  • III. Newer Concepts of Cerebral Glucose Metabolism in Vivo
  • IV. Disorders of Glucose Metabolism in Brain
  • References
  • 5 Effects of Viral Infections on the Brain
  • I. Introduction
  • II. Methods
  • III. Pathways of Viral Spread
  • IV. Cellular Response to Viral Infection
  • V. Biochemical Changes
  • VI. Immunological Reactions
  • VII. Pathogenesis of Viral Diseases of the Brain
  • VIII. Conclusion
  • References
  • 6 Disorders of Cerebrospinal Fluid and Brain Extracellular Fluid
  • I. Introduction
  • II. Anatomical Considerations
  • III. Pathophysiological Aspects of Cerebrospinal Fluid
  • IV. Pathophysiological Aspects of Brain Extracellular Fluid
  • References
  • 7 Disorders of Nucleic Acid Metabolism
  • I. Disorders of Purine Metabolism
  • II. Disorders of Pyrimidine Metabolism
  • References
  • 8 Effects of Malnutrition on Brain Development
  • I. Introduction
  • II. General Considerations Involved in Cellular Growth
  • III. Normal Cellular Growth of the Brain
  • IV. Nutritional Effects on Cellular Growth of the Brain
  • V. Prenatal Malnutrition
  • VI. Summary
  • References
  • 9 Pathophysiology of Anoxic Brain Damage
  • I. Introduction
  • II. Normal Oxidative Metabolism in the Brain
  • III. Work Performed by the CNS Cells
  • IV. Supply of Oxygen to the Brain Cells
  • V. Supply and Metabolism of Substrates
  • VI. Energy Flow and Energy State
  • VII. Measurements of Energy States and Metabolite Levels
  • VIII. Types of Cerebral Hypoxia and Anoxia
  • IX. Cerebral Changes in Anoxia and Hypoxia
  • X. Cerebral Changes in Ischemia
  • XI. Factors Modifying the Response to Anoxia
  • References
  • 10 Effects of Deficiencies of Folic Acid and Vitamin B12 on Central Nervous System Function and Development
  • I. Introduction
  • 1 Genetic Disorders of Mucopolysaccharide Metabolism
  • I. Introduction
  • II. Classification of the Disorders
  • III. Genetics
  • IV. Chemical Pathology
  • V. Chemistry of the Sulfated Mucopolysaccharides
  • VI. The Biochemical Defect
  • VII. Some Practical Applications of Recent Biochemical Findings
  • VIII. Summary
  • Note Added in Proof
  • References
  • 2 Galactosemia: Biochemistry, Genetics, Pathophysiology, and Developmental Aspects
  • I. Introduction
  • II. Galactose Metabolism
  • III. Hereditary Enzymatic Deficiencies in Galactose Metabolism
  • IV. The Pathophysiology of Galactosemia
  • V. Treatment
  • References
  • 3 Cytogenetic Aspects of Brain Dysfunction
  • I. Introduction
  • II. Incidence of Human Chromosome Anomalies
  • III. Syndromes Related to Autosomal Abnormalities
  • IV. Syndromes Related to Sex Chromosome Abnormalities
  • V. Syndromes Related to Chromosome Breakages
  • VI. Detection of Individuals with Abnormal Chromosomes