Issues and Reviews in Teratology Volume 2
A growing sophistication of the American populace about the nature and realities of the impact of the environment on prenatal development was not much in evi dence in 1983. Continuing accusations against Agent Orange and Bendectin high light what must be a deep credulousness and need to blame othe...
Other Authors: | |
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Format: | eBook |
Language: | English |
Published: |
New York, NY
Springer US
1984, 1984
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Edition: | 1st ed. 1984 |
Subjects: | |
Online Access: | |
Collection: | Springer Book Archives -2004 - Collection details see MPG.ReNa |
Table of Contents:
- 13. Fetal Sensitivity in Animals Relative to Humans: Conclusions
- 14. Summary
- References
- 5 Transplacental Exposure to Diethylstilbestrol
- 1. Introduction
- 2. Clinical Research
- 3. Animal Research
- 4. Mechanism of Transplacental Carcinogenesis
- References
- 6 Hormones, Growth Factors, and Their Receptors in Normal and Abnormal Prenatal Development
- 1. Introduction
- 2. Steroids
- 3. Growth Hormones and Factors
- 4. Dioxins and Their Receptors in Teratology
- 5. Benzodiazepine and Opiate Receptors
- 6. Summary and Conclusions
- References
- 7 Vertebrate Limb Morphogenesis: A Review of Normal Development in a Model Experimental System with Applications toward Understanding Abnormal Limb Formation
- 1. Introduction
- 2. The Apical Ectodermal Ridge
- 3. Mesoderm and Limb Patterns
- 4. Extracellular Matrix
- 5. Cell Death
- 6. Limb Mutants
- 7. Dysmorphogenesis
- 8. Summary
- References
- 8 Teratogenicity of Experimental and Occupational Exposure to Industrial Chemicals
- 1. Introduction
- 2. Alcohols (Ethanol)
- 3. Aldehydes
- 1 Birth Defects Monitoring Systems: Accomplishments and Goals
- 1. Introduction
- 2. Further Reasons for Registering Malformations
- 3. Fundamentals of Malformation Registration
- 4. What Should Be Monitored?
- 5. The Problem of Ascertainment
- 6. Size of Population Monitored
- 7. Properties of Monitoring Systems and Ascertainment Rates
- 8. Detection of Changes in Prevalence
- 9. Limitations and Benefits of Monitoring Systems
- References
- 2 What Is a Teratogen? Epidemiological Criteria
- 1. Introduction
- 2. Definition of a Teratogen
- 3. Criteria of Judgment in Epidemiology
- 4. Dealing with Doubt
- 5. Raising the Alert
- 6. Conclusion
- References
- 3 Congenital Hydrocephalus in Mice and Man
- 1. Introduction
- 2. Teratology
- 3. Discussion
- References
- 4 Congenital Defects of Domestic and Feral Animals
- 1. Introduction
- 2. Definitions
- 3. Nature and Effect
- 4. Frequency
- 5. Causes
- 6. Specific Defects
- 7. Conclusions
- References
- 4. Heavy Metals
- 5. Halogenated Hydrocarbons (Chlorinated Solvents)
- 6. Ketones
- 7. Organic Solvents
- 8. Plastics and Related Chemicals
- 9. Chlorobenzenes and Carbon Monoxide
- 10. Discussion and Conclusions
- References
- 9 Critical Assessment of Genetic Effects of Ionizing Radiation on Pre- and Postnatal Development
- 1. Introduction
- 2. Prologue
- 3. The Human Experience
- 4. Permissible Exposures
- 5. Future Directions
- 6. Glossary
- References
- 10 Adverse Effects in Humans and Animals of Prenatal Exposure to Selected Therapeutic Drugs and Estimation of Embryo-Fetal Sensitivity of Animals for Human Risk Assessment: A Review
- 1. Introduction
- 2. Aspirin and Salicylates
- 3. Progestational Agents
- 4. Anticonvulsant Drugs
- 5. Phenothiazines
- 6. Meprobamate
- 7. Pregnancy Toxemia and Reserpine
- 8. Thalidomide
- 9. Isoniazid
- 10. Tetracyclines
- 11. Aminopterin
- 12. Methotrexate