Clinical Applications of Cytokines and Growth Factors

The hematopoietic system plays roles that are crucial for survival of the host: delivery of oxygen to tissues, arrest of accidental blood leaking from blood vessels, and fending off of invading microbes by humoral, cell-mediated, and phagocytic immunity. The activity of the hematopoietic system is s...

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Bibliographic Details
Other Authors: Wingard, John R. (Editor), Demetri, George D. (Editor)
Format: eBook
Language:English
Published: New York, NY Springer US 1999, 1999
Edition:1st ed. 1999
Series:Developments in Oncology
Subjects:
Online Access:
Collection: Springer Book Archives -2004 - Collection details see MPG.ReNa
Table of Contents:
  • 21. The Use of Cytokines to Enhance Collection of Stem Cells for Marrow and Blood Transplantation
  • 22. The Use of Cytokines During Blood and Marrow Transplantation
  • I. Biology of Hematopoietic and Lymphopoietic Cytokines
  • 1. Cytokines, Growth Factors, and Hematopoiesis
  • 2. The Interaction of Cytokines with Stem Cell and Stromal Cell Physiology
  • 3. The Interaction of Cytokines with T-cell and Natural Killer Cell Physiology
  • 4. Improving on Nature by Re-Engineering Hematopoietic Growth Factors
  • II. Management of Neutropenia and Neutropenic Fever
  • 5. The Influence of Colony Stimulating Factors on Neutrophil Production, Distribution, and Function
  • 6. Evidence-Based Use of Hematopoietic Cytokines in Clinical Oncology
  • 7. Economic, Public Health, and Policy Implications of Hematopoietic Growth Factors, High-Dose Chemotherapy, and Stem Cell Rescue
  • 8. Outpatient Management of Neutropenic Fever: Antibiotics, Growth Factors or Both?
  • 9. The Use of Hematopoietic Growth Factors for Recruitment of Leukocytes for Transfusion
  • III. Management of Anemia
  • 10. Pathophysiology of the Anemia of Malignancy
  • 11. The Use of Recombinant Erythropoietin in the Treatment and Prevention of Cancer and Chemotherapy Related Anemia
  • IV Management of Thrombocytopenia
  • 12. Regulation of Human Megakaryocytopoiesis
  • 13. The Effects of Multilineage Cytokines on Platelet Recovery
  • 14. Clinical Studies of Thrombopoietin
  • V. The Role of Cytokines to Enhance Cancer Chemotherapy
  • 15. Dose Intensification in Solid Tumor Chemotherapy
  • 16. Conventional and High Dose Chemotherapy for Lymphomas
  • 17. Hematopoietic Growth Factors in Acute Leukemia
  • VI. Management of Marrow Failure States
  • 18. Cytokines for the Treatment of Myelodysplastic Syndromes and Other Bone Marrow Failure States
  • VII The Use of Cytokines in Blood and Marrow Transplantation
  • 19. Stem Cell Collection for Hematopoietic Transplantation: Stem Cell Sources, Mobilization Strategies, and Factors that Influence Yield
  • 20. Mechanisms of Growth Factor Mobilization of Hematopoietic Progenitors