Copper Transport and Its Disorders Molecular and Cellular Aspects

This book is a compilation of presentations at the first meeting devoted to the mo­ lecular and cellular biology of copper transport. When we first considered the possible program for the meeting, we felt that a forum to integrate the recent advances in molecular understanding of copper transport wi...

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Bibliographic Details
Other Authors: Leone, Arturo (Editor), Mercer, Julian F.B. (Editor)
Format: eBook
Language:English
Published: New York, NY Springer US 1999, 1999
Edition:1st ed. 1999
Series:Advances in Experimental Medicine and Biology
Subjects:
Online Access:
Collection: Springer Book Archives -2004 - Collection details see MPG.ReNa
Table of Contents:
  • 1. Copper Transport in Mammals
  • 2. Models to Evaluate Health Risks Derived from Copper Exposure/Intake in Humans
  • 3. Cu Metabolism in the Liver
  • 4. Multiple Forms of the Menkes Cu-ATPase
  • 5. The Cell Biology of the Menkes Disease Protein
  • 6. Functional Analysis of the Menkes Protein (MNK) Expressed from a cDNA Construct
  • 7. Mutation Spectrum of ATP7A, the Gene Defective in Menkes Disease
  • 8. Animal Models of Menkes Disease
  • 9. Developmental Expression of the Mouse Mottled and Toxic Milk Genes
  • 10. The Treatment of Wilson’s Disease
  • 11. Indian Childhood Cirrhosis and Tyrolean Childhood Cirrhosis: Disorders of a Copper Transport Gene?
  • 12. Animal Models of Wilson’s Disease
  • 13. Copper-Binding Properties of the N-Terminus of the Menkes Protein
  • 14. Expression, Purification, and Metal Binding Characteristics of the Putative Copper Binding Domain from the Wilson Disease Copper Transporting ATPase (ATP7B)
  • 15. Structure/Function Relationships in Ceruloplasmin
  • 16. Autoxidation of Amyloid Precursor Protein and Formation of Reactive Oxygen Species
  • 17. Copper-Zinc Superoxide Dismutase and ALS
  • 18. A Study of the Dual Role of Copper in Superoxide Dismutase as Antioxidant and Pro-Oxidant in Cellular Models of Amyotrophic Lateral Sclerosis
  • 19. The Effect of Copper on Tight Junctional Permeability in a Human Intestinal Cell Line (Caco-2)
  • 20. Metal Regulation of Metallothionein Gene Transcription in Mammals
  • 21. Copper-Regulatory Domain Involved in Gene Expression
  • 22. Intracellular Pathways of Copper Trafficking in Yeast and Humans
  • 23. Copper Homeostasis in Enterococcus hirae