Iron Chelation Therapy
Within the last few years, iron research has yielded exciting new insights into the under standing of normal iron homeostasis. However, normal iron physiology offers little protec tion from the toxic effects of pathological iron accumulation, because nature did not equip us with effective mechanis...
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| Format: | eBook |
| Language: | English |
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New York, NY
Springer US
2002, 2002
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| Edition: | 1st ed. 2002 |
| Series: | Advances in Experimental Medicine and Biology
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| Subjects: | |
| Online Access: | |
| Collection: | Springer Book Archives -2004 - Collection details see MPG.ReNa |
Table of Contents:
- Pathopysiology of Iron Overload
- 1.Animal Models of Hereditary Iron Transport Disorders
- 2.Mechanism of Iron Toxicity
- 3.Role of Non-Transferrin-Bound Iron in the Pathogenesis of Iron Overload and Toxicity
- 4.Intacellular and Extracellular Labile Iron Pools
- 5.Cardioprotective Effect of Iron Chelators
- Chelation Therapy in Transfulional Siderosis
- 6.Results of Long Term Iron Chelation Treatment with Deferoxamine
- 7.Long Term Deferiprone Chelation Therapy
- Development of New Iron Chelators
- 8.Iron Chelator Chemistry
- 9.Structure-Activity Relationships Among Desazadesferrithiocin Analogues
- 10.ICL670A: Preclinical Profile
- 11.Pyridoxal Isonicotinoyl Hydrazone and Its Analogues
- Novel Strategies in Iron Chelation Treatment
- 12.Therapeutic Potential of Iron Chelators in Cancer Therapy
- 13.Antimalarial Effect of Iron Chelators