Metabolic Profiling: Its Role in Biomarker Discovery and Gene Function Analysis

It is evident that biochemical control is not strictly hierarchical and that intermediary metabolism can contribute to control of regulatory pathways. Metabolic studies are therefore increasingly important in gene function analyses, and an increased interest in metabolites as biomarkers for disease...

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Bibliographic Details
Other Authors: Harrigan, George G. (Editor), Goodacre, Royston (Editor)
Format: eBook
Language:English
Published: New York, NY Springer US 2003, 2003
Edition:1st ed. 2003
Subjects:
Online Access:
Collection: Springer Book Archives -2004 - Collection details see MPG.ReNa
Description
Summary:It is evident that biochemical control is not strictly hierarchical and that intermediary metabolism can contribute to control of regulatory pathways. Metabolic studies are therefore increasingly important in gene function analyses, and an increased interest in metabolites as biomarkers for disease progression or response to therapeutic intervention is also evident in the pharmaceutical industry. This book offers guidelines to currently available technology and bioinformatics and database strategies now being developed. Evidence is presented that metabolic profiling is a valuable addition to genomics and proteomics strategies devoted to drug discovery and development, and that metabolic profiling offers numerous advantages
Physical Description:XIV, 335 p online resource
ISBN:9781461503330