White cells and platelets in blood transfusion Proceedings of the Eleventh Annual Symposium on Blood Transfusion, Groningen 1986, organized by the Red Cross Blood Bank Groningen-Drenthe

As a clinical discipline blood transfusion encompasses enormous vista, vary­ ing from biotechnology to molecular biology, from plasma products, cell biology and growth factors to interleukines. Growth of knowledge in this field has been rapid, and expertise is now required to be mastered and renewed...

Full description

Bibliographic Details
Other Authors: Smit Sibinga, C.Th (Editor), Das, P.C. (Editor), Engelfriet, C.P. (Editor)
Format: eBook
Language:English
Published: New York, NY Springer US 1987, 1987
Edition:1st ed. 1987
Series:Developments in Hematology and Immunology
Subjects:
Online Access:
Collection: Springer Book Archives -2004 - Collection details see MPG.ReNa
Table of Contents:
  • I. Principles and functional aspects
  • The human MHC (HLA) and immediate relevance in transfusion Practice
  • Alloimmunization against platelets and granulocytes
  • Leukocytes in transfusion medicine — an overview of functions and clinical implications
  • Platelet functions and platelet transfusion
  • Discussion
  • II. Clinical Aspects
  • A.Presence of cells
  • Platelet transfusion
  • Prospective selection of compatible platelet donors for alloimmunized patients by an ELISA platelet cross-match only
  • White blood cell transfusions in the immuno-compromised patients
  • Immunization with antigen-bound antibody: an experimental approach to prevention of sensitization to allogeneic blood cells
  • Autologous bone marrow transplantation in acute myeloblastic leukemia (AML): in vitro studies to detect minimal disease in remission marrow
  • Autologous bone marrow transplantation in solid malignancies
  • Discussion
  • Clinical use of leukocyte poor red cell concentrates
  • Management and prevention of cytomegalovirus infection
  • Graft-versus-Host disease and the role of blood product irradiation
  • Perspectives for lymphokine therapy: from genetic engineering to immunologic engineering
  • Discussion
  • III. Production aspects
  • Practical aspects of platelet concentrate production and storage
  • Surge plateletapheresis
  • Platelets and propylene glycol: an approach to freezing platelets in the presence of a new cryoprotectant
  • Bacterial contamination in platelets stored at ambient temperature
  • Preparation of leukocyte-poor blood
  • Use of hemapheresis-derived hemopoietic stem cells for transplantation in malignant lymphohemopoietic disorders
  • Purging of bone marrow
  • Discussion
  • IV. Laboratory aspects
  • HLA-matching and crossmatching in platelet transfusion
  • Cell culture and immune functiontests
  • Platelet antibody detection
  • Decreased fluidity of human platelet membranes after interaction with an anti PLA1 antibody
  • Role of white cells in reagents for AIDS
  • Discussion