Biotechnology in blood transfusion Proceedings of the Twelfth Annual Symposium on Blood Transfusion, Groningen 1987, organized by the Red Cross Blood Bank Groningen-Drenthe

This symposium is devoted to Biotechnology in Blood Transfusion; there are 22 experts discussing the state of the art in the application of monoclonal anti­ bodies, recombinant DNA technologies and heterologous expression systems to the improvement and sometimes replacement of blood products, charac...

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Bibliographic Details
Other Authors: Smit Sibinga, C.Th (Editor), Das, P.C. (Editor), Overby, L.R. (Editor)
Format: eBook
Language:English
Published: New York, NY Springer US 1988, 1988
Edition:1st ed. 1988
Series:Developments in Hematology and Immunology
Subjects:
Online Access:
Collection: Springer Book Archives -2004 - Collection details see MPG.ReNa
Table of Contents:
  • I. Fundamentals of biotechnology
  • Opportunities for biotechnology in transfusion medicine
  • to molecular genetics and recombinant DNA technology
  • Molecular genetic analysis of HLA class II polymorphism
  • Bioengineering in blood transfusion medicine
  • Discussion
  • II. Laboratory application of biotechnology
  • Biotechnology in glood group serology — Application and trends for the future
  • The characterization of monoclonal antibodies directed against carbohydrate epitopes by immunochemical means; the importance of such monoclonal antibodies for the recognition of blood group antigens
  • Biochemistry of HLA-B27 in transfected cells and transgenic mice
  • Biotechnology in the development of HIV diagnostic procedures
  • Biotechnology and the development of HBV diagnostic procedures
  • Monoclonal antibodies in blood coagulation
  • Discussion
  • III. Biotechnology and blood components
  • Monoclonal antibodies in the production of purified proteins from human plasma
  • Production of clotting factors through biotechnology
  • Mammalian cell expression and characterization of recombinant human antitrhombin III
  • Production and testing of rDNA hepatitis B vaccine
  • Production and application of monoclonal antibodies in T-cell depletion of bone marrow for transplantation
  • LAK cell production: Application of rDNA and cell culture technology
  • Biotechnology of hemopoietic cells in culture
  • Discussion
  • IV. Clinical application and future directions
  • Use of gene probes for carrier detection and prenatal diagnosis in hemophillia A
  • In vivo characteristics of rDNA Factor VIII: The impact for the future in hemophilia care
  • Clinical experience with monoclate®, a monoclonal antibody purified Factor VIII preparation from human plasma
  • Depletion of lymphocytes from bone marrow —indications, expectations and clinical experience
  • Hematopoietic hormones in transfusion medicine
  • Discussion