Biomedical Advances in Aging

The VIIIth Annual International Spring Symposium on Health Sciences held at the George Washington University School of Medicine in Washington, D.C., attracted over three hun­ dred fifty scientists from twenty-five countries. The leading scientific experts in the field reported on recent biomedical a...

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Bibliographic Details
Other Authors: Goldstein, Allan L. (Editor)
Format: eBook
Language:English
Published: New York, NY Springer US 1990, 1990
Edition:1st ed. 1990
Series:Gwumc Department of Biochemistry and Molecular Biology Annual Spring Symposia
Subjects:
Online Access:
Collection: Springer Book Archives -2004 - Collection details see MPG.ReNa
Table of Contents:
  • 17. Altered Phosphatidylinositol Breakdown in Polymorphonuclear Leukocytes with Aging
  • 18. Rejoining of X-Ray-Induced DNA Double-Strand Breaks Declines in Unstimulated Human Lymphocytes Aging in Vivo
  • 19. Interventive Gerontology, Cloning, and Cryonics: Relevance to Life Extension
  • 20. Effects of Various Stimulators and Inhibitors on the Respiratory Burst of PMNL with Aging
  • 21. Quantitative Approaches to Pathogenesis of Age-Related Metabolic Conditions
  • III—Role of Nutritional, Dietary, and Immune Factors in the Pathogenesis of Aging
  • 22. Nutritional Requirements in Aging
  • 23. Influence of Dietary Restriction and Aging on Gene Expression in the Immune System of Rats
  • 24. Zinc, Immunity, and Aging
  • 25. Neuroendocrine Effects of Lifelong Dietary Restriction by Intermittent Feeding in Mice
  • 26. Age-Associated Decline in Renal Response to Vasopressin: Diminished Adenylate Cyclase Activation in Collecting Ducts
  • 40. Regulation of the Expressed Idiotypic Repertoire in the Normal Immune Response of the Aged
  • 41. Analysis of the Ability of Spleen Cells from Aged Mice to Produce Allospecific Cytotoxic Cells
  • V—The Brain, Neuroendocrine Circuits, Pathology, and Plasticity
  • 42. Neuronal Populations in Normal and Abnormal Aging
  • 43. An Optimistic View of the Aging Brain
  • 44. Complex Maze Learning in Rodents: Progress and Potential for Modeling Age-Related Memory Dysfunction
  • 45. Age-Related Changes in Brain Protein Kinase C and Serotonin Release
  • 46. Increased Blood Flow Augments CNS Axon Regeneration
  • 47. Free and Bound Polyamines in Normal and Alzheimer Temporal Cortex
  • 48. Neurochemical and Behavioral Effects of Bilateral Nucleus Basalis Lesions in the Aged Rat
  • 49. Dopaminergic Neurons in the Substantia Nigra in Normal Aging and MPTP-Lesioned Mice
  • 50. Synaptic Plasticity and Aging
  • I—Molecular Biology, Virology, and Genetics of Alzheimer’s Disease
  • 1. Brain Amyloidoses: Precursor Proteins and the Amyloids of Transmissible and Nontransmissible Dementias: Scrapie-Kuru-CJD Viruses as Infectious Polypeptides or Amyloid-Enhancing Factors
  • 2. Prions Causing Neurodegenerative Diseases: Immunoaffinity Purification and Neutralization of Scrapie Infectivity
  • 3. The Molecular Genetics of Alzheimer’s Disease
  • 4. A Developmental Genetic Approach to the Analysis of Aging Processes
  • 5. Alzheimer’s Disease: Enter Protein Chemistry
  • 6. Evidence for the Molecular Basis of Aging and Sequestration of Mammalian Erythrocytes
  • 7. ?1-Antichymotrypsin: The Role of Proteases and Their Inhibitors in the Amyloid Deposition of Alzheimer’s Disease and Normal Brain Aging
  • 8. Replication of Adenovirus 2 and Adeno-Associated Virus 2 in Young and Senescent Human Diploid Fibroblasts
  • 27. Obesity and Lipoproteins: Influence of Weight Reduction in Postmenopausal Woman
  • 28. Phenotype and Function of Lymphocyte Clones from Old and Young Subjects
  • 28. Calorie Restriction and Longevity
  • 29. Effect of Dietary Linolenate on the Pathogenesis of Fever
  • 30. Poor Early Growth and Adult Mental and Somatic Health
  • IV—Immunological Components and Immunoregulation in Aging
  • 32. Alterations in B Cells and Antibodies of Aged Mice
  • 33. Molecular Genetic Analysis of Human Monoclonal Gammopathies
  • 34. Developmental Aspects of T Lymphocytes in Aging
  • 35. Role of the Thymus in Aging of the Immune System
  • 36. Modulation of T-Cell Functions in Aging
  • 37. Age-Related Decline in Immunological Resistance to Infection: Murine Trypanosomiasis as a Model
  • 38. The Clinical Significanceof Immune Senescence: Advantages and Disadvantages
  • 39. Immunosenescence and Human NK Cells
  • VI—Immunological, Endocrine, and Pharmacological Approaches to Treatment of Diseases of Aging
  • 51. Influenza and Aging: Immunological Methods of Enhancing Influenza Vaccine Response in Elderly People
  • 52. Age-Dependent Enhancement of Influenza Vaccine Responses by Thymosin in Chronic Hemodialysis Patients
  • 53. Lipid and Lipoprotein Changes Due to Estrogen Replacement Therapies and Their Association with Prevention of Cardiovascular Disease in Postmenopausal Women
  • 54. Immunopotentiating Activity of Thymopentin Treatment in Elderly Subjects
  • 55. Thymopentin Therapy in Elderly Patients with Chronic Bronchitis: A Clinical and Cellular Study
  • 56. Aspirin and Risks of Cardiovascular Disease in the Physicians’ Health Study
  • Participants
  • 9. Lactoferrin Immunoreactivity and Binding Sites in Neurons, Neuritic Plaques, and Neurofibrillary Tangles in Alzheimer’s Disease
  • 10. Immunological Investigation of Thymic-Dependent Immunity in Normal Aging and in Patients with Senile Dementia of Alzheimer Type
  • II—Metabolic, Membrane, and Cellular Markers and Models
  • 11. Chronic Diseases and Disorders: A Hypothesis Suggesting an Age-Dependent versus an Age-Related Class
  • 12. Changes in Receptors and Signal Transduction Events during Aging
  • 13. Molecular Aging of Membrane Molecules and Cellular Removal
  • 14. Health Watch: A Longitudinal Prospective Study of Healthy Aging in 2200 Individuals: I. Preliminary Analysis of Biochemical, Hematological, and Physiological Data for Males and Females. Application to the Care of Older Patients
  • 15. Plasma ?-Tocopherol Levels in Men and Women of Different Ages
  • 16. Polyenoic FattyAcid Metabolism and Prostaglandin Biosynthesis in Aged Persons