The Use of Restricted Significance Tests in Clinical Trials

The reader will soon find that this is more than a "how-to-do-it" book. It describes a philosophical approach to the use of statistics in the analysis of clinical trials. I have come gradually to the position described here, but I have not come that way alone. This approach is heavily infl...

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Bibliographic Details
Main Author: Salsburg, David S.
Format: eBook
Language:English
Published: New York, NY Springer New York 1992, 1992
Edition:1st ed. 1992
Series:Statistics for Biology and Health
Subjects:
Online Access:
Collection: Springer Book Archives -2004 - Collection details see MPG.ReNa
Table of Contents:
  • One Philosophical and Scientific Problems when Applying Statistical Methods to Clinical Data
  • 1 The Randomized Controlled Clinical Trial
  • 2 Probability Models and Clinical Medicine
  • 3 Significance Tests Versus Hypothesis Tests
  • 4 Neyman’s Insights
  • 5 Reconciling Fisher and Neyman
  • Two Techniques for Applying Restricted Tests to Data from Randomized Controlled Clinical Trials
  • 6 Continuous Measures Taken over Time
  • 7 Combining Data Across Measures
  • 8 Counts of Events
  • 9 Permutation Tests and Resampling Techniques
  • 10 Neyman’s Restricted Chi Square Tests
  • 11 Miscellaneous Methods for Increasing Power
  • 12 Bayesian Estimation
  • 13 An Example of the Type of Analysis Suggested in This Book
  • References