Genetic Models of Immune and Inflammatory Diseases
This book contains the proceedings of the Serono Symposia USA interna tional symposium on Genetic Models of Immune and Inflammatory Dis eases held on October 20 to 23, 1994, in Savannah, Georgia. The advent of methods for introducing genes into the germlines of mice, and for targeted disruption of...
| Other Authors: | , |
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| Format: | eBook |
| Language: | English |
| Published: |
New York, NY
Springer New York
1996, 1996
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| Edition: | 1st ed. 1996 |
| Series: | Serono Symposia USA
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| Subjects: | |
| Online Access: | |
| Collection: | Springer Book Archives -2004 - Collection details see MPG.ReNa |
Table of Contents:
- I. Autoimmunity
- 1. Intensification of Diabetes in B7-1 Transgenic Mice
- 2. A Transgenic Window on Self-Reactive T Lymphocytes
- 3. Induction and Breaking of Peripheral Tolerance
- 4. T-Cell Development and Tolerance in Virus-Specific Transgenic Models
- 5. Inflammatory Disease in HLA-B27 Transgenic Rats
- II. Autoimmunity, Infections
- 6. The Role of CD40 Ligand in Regulation of Immune Response
- 7. Adventures in Antigen Presentation
- 8. The Effect of MHC Encoding Transgenes on IDDM in NOD Mice
- 9. The Immunology of Leishmania Major Infection in Mice
- III. Cytokines, Co-Stimulators, Tumor Immunity
- 10. The Regulatory Functions of Co-Stimulators Revealed in Transgenic Mice
- 11. B7-Deficient Mice Reveal an Alternative Functional CTLA-4 Counterreceptor
- 12. Cytokine Transgenic Mice and Autoimmunity
- 13. Gaining Insights into the Ontogeny and Activation of T Cells Through the Use of Gene-Targeted Mutant Mice
- 14. B7-Mediated Co-Stimulation of T Cells: CTLA-4 Can Deliver Inhibitory Signals
- IV. Cytokine Deletions
- 15. Lymphoid Organogenesis and Inflammation Are Mediated by Lymphotoxin
- 16. The Role of Interferon-? in the Development of Type I Diabetes
- 17. Cytokine-Deficient Mouse Mutants
- Author Index