Antibiotic Resistance

This book describes antibiotic resistance amongst pathogenic bacteria. It starts with an overview of the erosion of the efficacy of antibiotics by resistance and the decrease in the rate of replacement of redundant compounds. The origins of antibiotic resistance are then described. It is proposed th...

Full description

Bibliographic Details
Other Authors: Coates, Anthony R.M. (Editor)
Format: eBook
Language:English
Published: Berlin, Heidelberg Springer Berlin Heidelberg 2012, 2012
Edition:1st ed. 2012
Series:Handbook of Experimental Pharmacology
Subjects:
Online Access:
Collection: Springer eBooks 2005- - Collection details see MPG.ReNa
Table of Contents:
  • Preface
  • Introduction to antibiotic resistance
  • Origins of antibiotic resistance
  • Surveillance Programs and Antibiotic Resistance: Worldwide and Regional Monitoring of Antibiotic Resistance Trends
  • Current and future challenges in the development of antimicrobial agents
  • Resistance in Gram-negative bacteria
  • Non-multiplying bacteria are profoundly tolerant to antibiotics
  • Prevention of drug resistance by multidrug treatment of tuberculosis
  • Persister cells–molecular mechanisms related to antibiotic tolerance
  • Antimicrobial textiles
  • Efflux – how bacteria use pumps to control their micro-environment
  • Antibiotics in Phase II and III clinical trials