Free-Radical-Induced DNA Damage and Its Repair A Chemical Perspective
Understanding of the molecular basis of DNA damage and its repair has increased dramatically in recent years, and substantial knowledge now exists concerning the products arising from free-radical attack on DNA. Free-radical DNA damage may lead to mutations, cancer, and cell death. Free radicals hav...
Main Author: | |
---|---|
Format: | eBook |
Language: | English |
Published: |
Berlin, Heidelberg
Springer Berlin Heidelberg
2006, 2006
|
Edition: | 1st ed. 2006 |
Subjects: | |
Online Access: | |
Collection: | Springer eBooks 2005- - Collection details see MPG.ReNa |
Table of Contents:
- Formation of Reactive Free Radicals in an Aqueous Environment
- The Hydroxyl Radical
- Hydrogen Atom and Hydrated Electron
- Inorganic Radicals
- Carbon-Centered Radicals
- Heteroatom-Centered Radicals
- Peroxyl Radicals
- Polymer Radicals
- Nucleobases, Nucleosides and Nucleotides
- Polynucleotides and Single-Stranded DNA Fragments
- DNA and Double-Stranded Oligonucleotides
- Methods