Animal Models of T Cell-Mediated Skin Diseases
Pharmaceutical companies are spending increasing amounts of money on drug discovery and development. Nevertheless, attrition rates in clinical development are still very high, and up to 90% of new compounds fail in clinical phase I - III trials, which is partially due to lack of clinical efficacy. T...
| Other Authors: | , , |
|---|---|
| Format: | eBook |
| Language: | English |
| Published: |
Berlin, Heidelberg
Springer Berlin Heidelberg
2005, 2005
|
| Edition: | 1st ed. 2005 |
| Series: | Ernst Schering Foundation Symposium Proceedings
|
| Subjects: | |
| Online Access: | |
| Collection: | Springer eBooks 2005- - Collection details see MPG.ReNa |
Table of Contents:
- Making Gene-Modified Mice
- High-Throughput Gene Knockouts and Phenotyping in Mice
- Modelling Gene-Environment Interactions in Th1- and Th2-Dominated Diseases of Laboratory Animals
- Animal Models of Experimental Asthma
- Models of Rheumatoid Arthritis
- Animal Models of Inflammatory Bowel Diseases
- Murine Models of Atopic Dermatitis
- Epicutaneous Sensitization with Allergens as an Atopic Dermatitis Model
- T-Cell Receptor Transgenic Models of Inflammatory Disorders: Relevance for Atopic Dermatitis?
- What Must a Model Display for Proof as a Model of Psoriasis?
- From Classical Mouse Models of Psoriasis to a Spontaneous Xenograft Model Featuring Use of AGR Mice
- The Psoriasis SCID Mouse Model: A Tool for Drug Discovery?
- Pro- and Anti-inflammatory Effects of IL-4: From Studies in Mice to Therapy of Autoimmune Diseases in Humans
- What Must a Model Display for Proof as a Model of Contact Dermatitis?
- Acute and Chronic Models of Allergic Contact Dermatitis: Advantages and Limitations
- Transgenic Mice Expressing IFN-? in the Epidermis Are a Model of Inflammatory Skin Disease and Systemic Lupus Erythematosus