Infection, Immune Homeostasis and Immune Privilege

Organs and tissues that can tolerate little or no inflammation have developed multiple overlapping mechanisms of immune protection in the absence of inflammation. These areas have been designated “immune-privileged sites” by Peter Medawar and include the central nervous system, eye, reproductive tra...

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Corporate Author: SpringerLink (Online service)
Other Authors: Stein-Streilein, Joan (Editor)
Format: eBook
Language:English
Published: Basel Springer Basel 2012, 2012
Edition:1st ed. 2012
Series:Birkhäuser Advances in Infectious Diseases
Subjects:
Online Access:
Collection: Springer eBooks 2005- - Collection details see MPG.ReNa
Summary:Organs and tissues that can tolerate little or no inflammation have developed multiple overlapping mechanisms of immune protection in the absence of inflammation. These areas have been designated “immune-privileged sites” by Peter Medawar and include the central nervous system, eye, reproductive tract, testis and possibly the liver. Mechanisms of immune homeostasis found in less immune-regulated organs are often evident in the immune privileged sites and vice versa. It is important that the non-inflammatory mechanisms that contribute to immune privilege allow host defense against infectious organisms. This volume highlights the mechanisms leading to immune privilege in tissues and organs, the deviation of immune responses and the modification of the behavior of the immune cells that manage to cross the blood barriers of tissues, in the context of infection
Physical Description:XII, 156 p online resource
ISBN:9783034804455