Cancer Stem Cells in Solid Tumors

The “cancer stem cell” hypothesis postulates that cancer arises from a subpopulation of tumor-initiating cells or cancer stem cells (CSCs). While the idea of cancer stem cells has been around for more than a hundred years, evidence from the fields of hematology and cancer biology has now demonstrate...

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Bibliographic Details
Other Authors: Allan, Alison L. (Editor)
Format: eBook
Language:English
Published: Totowa, NJ Humana 2011, 2011
Edition:1st ed. 2011
Series:Stem Cell Biology and Regenerative Medicine
Subjects:
Online Access:
Collection: Springer eBooks 2005- - Collection details see MPG.ReNa
Table of Contents:
  • Cancer Stem Cells: Historical Perspectives and Lessons From Leukemia
  • Cancer Stem Cells in Breast Cancer
  • Cancer Stem Cells in Brain Cancer
  • Cancer Stem Cells in Colorectal Cancer
  • Cancer Stem Cells in Pancreatic Cancer
  • Cancer Stem Cells in Prostate Cancer
  • Cancer Stem Cells in Melanoma
  • Cancer Stem Cells in Lung Cancer
  • Cancer Stem Cells in Ovarian Cancer
  • Cancer Stem Cells in Hepatocellular Cancer
  • Cancer Stem Cells in Head and Neck Cancer
  • Relationship Between Regulatory Pathways in Pluripotent Stem Cells and Human Tumors
  • Influence of the Embryonic Microenvironment on Tumor Progression
  • The Epithelial-to-Mesenchymal Transition and Cancer Stem Cells
  • Application of Stem Cell Assays for the Characterization of Cancer Stem Cells
  • Zebrafish as a Model to Study Stem Cells in Development, Disease and Cancer
  • Imaging Cancer Stem Cells
  • Mouse Models for Studying Normal and Cancer Stem Cells
  • Cancer Stem Cells and Disease Prognosis
  • Mechanisms of Radioresistance in Cancer Stem Cells
  • The Role of ABC Transporters in Cancer Stem Cell Drug Resistance
  • Resistance to Endocrine Therapy in Breast Cancer: Are Breast Cancer Stem Cells Implicated?
  • Future Directions: Cancer Stem Cells as Therapeutic Targets
  • Final Thoughts: Complexity and Controversy Surrounding the “Cancer Stem Cell” Paradigm