Ocular Transporters in Ophthalmic Diseases and Drug Delivery

This exceptionally important new work represents recent discoveries and advancements in the study of ocular transporters and their roles in ocular physiology, pathology, and drug delivery. Transporters are found on the membranes of cells and play a key role in transmitting signals between cells. In...

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Bibliographic Details
Other Authors: Tombran-Tink, Joyce (Editor), Barnstable, Colin J. (Editor)
Format: eBook
Language:English
Published: Totowa, NJ Humana 2008, 2008
Edition:1st ed. 2008
Series:Ophthalmology Research
Subjects:
Online Access:
Collection: Springer eBooks 2005- - Collection details see MPG.ReNa
Table of Contents:
  • Transport in the Anterior Segment
  • Aquaporins and Water Transport in the Cornea
  • Roles of Corneal Epithelial Ion Transport Mechanisms in Mediating Responses to Cytokines and Osmotic Stress
  • Vitamin C Transport, Delivery, and Function in the Anterior Segment of the Eye
  • Transporters of the Ciliary Epithelium
  • Mechanisms of Aqueous Humor Formation
  • Lens Transporters
  • Membrane Transporters
  • Lens Na+, K+-ATPase
  • Transport Across the Blood–Retinal Barrier
  • Pathophysiology of Pericyte-containing Retinal Microvessels
  • Molecular Mechanisms of the Inner Blood-Retinal Barrier Transporters
  • Transport Across the Retinal Pigment Epithelium
  • Regulation of Transport in the RPE
  • Glucose Transporters in Retinal Pigment Epithelium Development
  • Ca2+ Channels in the Retinal Pigment Epithelium
  • Taurine Transport Pathways in the Outer Retina in Relation to Aging and Disease
  • P-Glycoprotein Expression and Function in the Retinal Pigment Epithelium
  • Transporters in the Retina
  • The Retinal Rod NCKX1 and Cone/Ganglion Cell NCKX2 Na+/Ca2+-K+ Exchangers
  • Excitatory Amino Acid Transporters in the Retina
  • Localization and Function of Gamma Aminobutyric Acid Transporter 1 in the Retina
  • Genetic Variants of Ocular Transporters
  • Biochemical Defects Associated with Genetic Mutations in the Retina-Specific ABC Transporter, ABCR, and Macular Degenerative Diseases
  • Glutamate Transporters and Retinal Disease and Regulation
  • Glutamate Transport in Retinal Glial Cells during Diabetes
  • Ocular Drug Delivery
  • The Emerging Significance of Drug Transporters and Metabolizing Enzymes to Ophthalmic Drug Design
  • Barriers in Ocular Drug Delivery
  • Ophthalmic Applications of Nanotechnology
  • Vitamin C Transporters in the Retina
  • The Plasma Membrane Transporters and Channels of CornealEndothelium