The Aetiology of Deep Venous Thrombosis : A Critical, Historical and Epistemological Survey

What we now call ‘deep venous thrombosis’ (DVT) has been studied in diverse ways during the last 200–300 years. Each of these approaches contributes to a full modern understanding of aetiology. Therefore, much of this book is a historical survey of the field. However, our remit is broader than the t...

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Main Authors: Malone, P. Colm, Agutter, Paul S. (Author)
Corporate Author: SpringerLink (Online service)
Format: eBook
Published: Dordrecht Springer Netherlands 2008, 2008
Edition:1st ed. 2008
Online Access:
Collection: Springer eBooks 2005- - Collection details see MPG.ReNa
Table of Contents:
  • A History of Haematological Research
  • Virchow and the Pathophysiological Tradition in the 19th Century
  • The Pathophysiological Tradition after Virchow
  • Interrupted Circulation: The ‘Stasis’ Hypothesis and the Significance of Venous Valves
  • Underperfusion of Valve Pockets and the Initiation of DVT
  • The Role of Endothelial Hypoxia in DVT
  • The Valve Cusp Hypoxia Hypothesis
  • Molecular Changes in the Hypoxic Endothelium
  • Cadaver Clots or Agonal Thrombi?