Smad Signal Transduction Smads in Proliferation, Differentiation and Disease
For the first time world-leading experts in the area of cellular signaling have joined to the production of a book on Smad signal transduction. Smads are the principal intracellular effectors of TGF-b family members that control numerous cellular responses with critical roles in development and in t...
| Other Authors: | , |
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| Format: | eBook |
| Language: | English |
| Published: |
Dordrecht
Springer Netherlands
2006, 2006
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| Edition: | 1st ed. 2006 |
| Series: | Proteins and Cell Regulation
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| Subjects: | |
| Online Access: | |
| Collection: | Springer eBooks 2005- - Collection details see MPG.ReNa |
Table of Contents:
- Molecular Evolution of Smad Proteins
- C. Elegans TGF-? Signaling Pathways
- Smads In Drosophila – Interpretation Of Graded Signals In Vivo
- Delineating the TGF-?/Smad-Induced Cytostatic Response
- Smads In Mesenchymal Differentiation
- Smad Proteins in Apoptotic and Survival Signaling
- TGF-?/SMAD Signaling in Epithelial to Mesenchymal Transition
- Genetic Disruptions within the Murine Genome Reveal Numerous Roles of the Smad Gene Family in Development, Disease, and Cancer
- Trafficking of Serine/Threonine Kinase Receptors and Smad Activation
- Nucleocytoplasmic Shuttling of Smad Proteins
- Structural Insights into Smad Function and Specificity
- Regulation of Smad Function by Phosphorylation
- Regulation of Smad Functions Through Ubiquitination and Sumoylation Pathways
- Smad Transcriptional Co-Activators and Co-Repressors
- Integration of Signaling Pathways Via Smad Proteins
- Interplays Between The Smad and Map Kinase Signaling Pathways
- Gene Expression Signatures of TGF-?/Smad-Induced Responses
- Systems Biology Approaches to TGF-?/Smad Signaling
- Inhibitory Smads: Mechanisms of Action and Roles in Human Diseases
- Alterations in Smad Signaling in Carcinogenesis
- TGF-? Receptor Kinase Inhibitors for the Treatment of Cancer
- TGF-? Receptor Kinase Inhibitors for Treatment of Fibrosis