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|a 9780387360058
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|a Bürkle, Alexander
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|a Poly(ADP-Ribosyl)ation
|h Elektronische Ressource
|c by Alexander Bürkle
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|a 1st ed. 2006
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|a New York, NY
|b Springer US
|c 2006, 2006
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|a XVII, 246 p
|b online resource
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|a Enzymes in Poly(ADP-Ribose) Metabolism -- PARP-2: Structure-Function Relationship -- Targeting the Poly (ADP-Ribose) Glycohydrolase (PARG) Gene in Mammals -- DNA Damage Signaling through Poly(ADP-Ribose) -- Roles of Poly(ADP-Ribose) Metabolism in the Regulation of Centrosome Duplication and in the Maintenance of Neuronal Integrity -- Functional Interactions of PARP-1 with p53 -- Dynamic Interaction between PARP-1, PCNA and p21waf1/cip1 -- PARP-1 as Novel Coactivator of NF-?B in Inflammatory Disorders -- PARP and Epigenetic Regulation -- PARP and the Release of Apoptosis-Inducing Factor from Mitochondria -- Genome Degradation by DNAS1L3 Endonuclease -- NAD: Metabolism and Regulatory Functions -- PARP-1 and the Shape of Cell Death -- Poly(ADP-Ribose) Polymerase (PARP) and Excitotoxicity -- Poly(ADP-Ribose) Polymerase and Ischemia-Reperfusion Injury -- Role of Poly(ADP-Ribose) Polymerase Activation in the Pathogenesis of Inflammation and Circulatory Shock -- Role of Poly-ADP-Ribosylation in Cancer Development -- PARP Inhibitors and Cancer Therapy -- Poly(ADP-Ribosyl)ation and Aging
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|a Cell Biology
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|a Medical Genetics
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|a Cytology
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|a Medical genetics
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|a Biochemistry
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|a Medical Microbiology
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|a Medical microbiology
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|a eng
|2 ISO 639-2
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|b Springer
|a Springer eBooks 2005-
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|a Molecular Biology Intelligence Unit
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|a 10.1007/0-387-36005-0
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|u https://doi.org/10.1007/0-387-36005-0?nosfx=y
|x Verlag
|3 Volltext
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|a 616.9041
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|a Poly(ADP-Ribosyl)ation comprises 19 chapters written by leading international experts in the field and is richly illustrated. Extensive bibliography is given in each chapter
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